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. 2020 Mar 17;14:9. doi: 10.3389/fninf.2020.00009

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Copyright © 2020 Callara, Magliaro, Ahluwalia and Vanello.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Workflow of the SmRG. (A) Manual or automatic seed selection. (B) Dip test to test for unimodality against multimodality on a MxNx3 crop centered on the seed. The threshold is determined with Otsu’s method or through the Mixture Model according to whether the distribution is multimodal or not. (C) 3D segmentation of a MxNx3 crop. (D) The regional maxima of the distance transform of the segmented MxNx3 crop are chosen as new seeds. (E) The procedure iterates until there are no more new seeds.