Table 5.
The Effect of AgNPs and Cefotaxime-CS-AgNPs Treatment on the Proliferative Percentage of MCF-7 and RPE-1 Cells at Different Concentrations and Times Intervals
| Treatments Groups μg/mL | Proliferative Percentage of Treated Cells Lines | |||
|---|---|---|---|---|
| RPE-1 Cells | MCF-7 Cells | |||
| After 24 hrs | After 48 hrs | After 24 hrs | After 48 hrs | |
| Untreated Cells | 98.2 ± 0.98 a | 94.8 ± 0.72a | 95.30 ± 0.75a | 97.54 ± 1.51a |
| AgNPs 3.0 | 78.50 ± 1.44 d | 72.8 ± 0.10c | 76.10 ± 0.95cd | 71.80 ± 0.66 c |
| AgNPs 6.0 | 70.80 ± 1.54 b | 62.8 ± 0.10 d | 65.60 ± 0.72e | 60.10 ± 1.67 d |
| AgNPs 12.0 | 64.60 ± 0.57 e | 50.40 ± 0.65 ef | 59.50 ± 0.37e | 53.10 ± 0.68 d |
| AgNPs 24.0 | 50.90 ± 1.09 c | 44.90 ± 0.79 f | 47.60 ± 0.54f | 39.30 ± 0.90 e |
| Cefotaxime-CS-AgNPs 3.0 | 97.60 ± 0.67 a | 93.44 ± 0.54 a | 94.60 ± 0.43a | 96.50 ± 0.57 a |
| Cefotaxime-CS-AgNPs 6.0 | 93.20 ± 0.72 a | 86.75 ± 0.52 b | 89.80 ± 0.75b | 86.5 ± 0.46 b |
| Cefotaxime-CS-AgNPs 12.0 | 87.61 ± 0.37 ab | 79.74 ± 0.56 bc | 81.60 ± 0.53c | 79.90 ± 0.77 bc |
| Cefotaxime-CS-AgNPs 24.0 | 79.20 ± 0.94 b | 74.52 ± 0.31c | 80.17 ± 0.95c | 73.10 ± 0.88 c |
Notes: Means with different superscripts (a, b, c, d, e, and f) between groups in the same column are significantly different at P< 0.05. Cell numbers were counted and data are expressed as the percentage of untreated control.