Table 3.
Characteristics Comparison Between COPD with or Without OSA
| Item | COPD Subject with OSA (70) | COPD Subject Without OSA (54) | p |
|---|---|---|---|
| WBC | 6.46 (4.96,8.41) | 6.52 (5.90,8.16) | 0.502 |
| Neutrophils, % | 66.50 (60.18,74.48) | 64.34 (57.01,76.70) | 0.573 |
| Eosinophils | 0.14 (0.08,0.25) | 0.12 (0.03,0.26) | 0.343 |
| Eosinophils, % | 2.10 (1.20,3.76) | 1.48 (0.33,4.08) | 0.146 |
| Total IgE (IU/mL) | 112.50 (35.98,221.00) | 110.00 (22.40,520.00) | 0.857 |
| CRP (ng/mL) | 1.17 (0.45,2.86) | 1.03 (0.25,2.45) | 0.157 |
| Total T cells | 68.70 (59.78,74.24) | 70.04 (60.26,76.82) | 0.363 |
| CD4+ T cells | 39.72 (32.36,43.51) | 38.22 (32.76,48.13) | 0.760 |
| CD8+ T cells | 29.10 (22.33,33.08) | 26.50 (22.38,38.14) | 0.693 |
| CD4/CD8 | 1.35 (0.97,1.66) | 1.47 (0.95,2.00) | 0.484 |
| FeNO | 13.00 (10.00,21.00) | 19.00 (8.00,36.00) | 0.464 |
| AHI | 12.00 (7.50,22.00) | 1.50 (0.00,3.00) | 0.000*** |
| SpO2min | 82.00 (78.00,85.00) | 85.00 (79.00,88.00) | 0.081 |
| T90 (%) | 11.00 (1.78,38.28) | 2.00 (0.00,7.40) | 0.002** |
Notes: Data presented as median with 25–75th percentiles. **p < 0.01; ***p < 0.001.
Abbreviations: COPD, chronic obstructive pulmonary disease; OSA, obstructive sleep apnea; WBC, white blood cells; IgE, Immunoglobulin E; CRP, C-reactive protein; FeNO, fractionated exhaled nitric oxide; AHI, apnea-hypopnea index; SpO2min, minimum peripheral capillary oxygen saturation; T90, total sleep time spent with oxygen saturation below 90%.