Table 4.

Survival Prediction: Pathways Sampled by Different Algorithms Ranked According to the Scoring Provided by GeneAnalytics

FRS		HS
Score	Top Pathways	Score	Top Pathways
9.87	Integrin Pathway	13.54	Integrin Pathway
8.96	Fatty Acid Beta-oxidation (peroxisome)	11.30	Sweet Taste Signaling
7.94	DREAM Repression &Dynorphin Expression	11.28	DREAM Repression &Dynorphin Expression
7.88	Signaling Events Mediated By HDAC Class II	11.13	RhoA Signaling Pathway
7.54	Type II Interferon Signaling (IFNG)	9.58	Signaling Events Mediated By HDAC Class II
7.19	Fatty Acid Biosynthesis (KEGG)	9.40	Androgen Receptor Signaling Pathway
6.93	Fatty Acyl-CoA Biosynthesis	9.39	CCR5 Pathway in Macrophages
RS		BN
Score	Top Pathways	Score	Top Pathways
9.90	TCR Signaling	7.87	Nucleotide-binding Domain, NLR Signaling
9.79	Androgen Receptor Signaling Pathway	7.39	Apoptosis and Autophagy
9.48	Presenilin-Mediated Signaling	7.20	C-MYC Transcriptional Repression
8.57	Ovarian Infertility Genes	6.82	NF-kB (NFkB) Pathway
8.34	DNA Damage Response (ATM Dependent)	6.19	Apoptosis Modulation and Signaling
8.14	Apoptotic Pathways in Synovial Fibroblasts	6.13	Apoptosis and Survival Caspase Cascade
8.02	Sweet Taste Signaling	5.69	Senescence and Autophagy in Cancer

Notes: Reproduced from: Cernea et al. Robust pathway sampling in phenotype prediction. Application to triple nagtive cancer. BMC Bioinformatics. In press.⁹⁶