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. 2020 Mar 4;20:359–372. doi: 10.1016/j.omtn.2020.02.011

Figure 8.

Figure 8

Fluorescent Imaging of siRNA-IRDye 700 in the Flank Tumor and in the Brain following Injection of GLH-19/GLH-20/siRNA-IRDye 700 Vesicles into the Tail Vein of Mice

In each time panel, left images are tumor (top) and brain (bottom), and right images show their fluorescence. Fluorescence imaging shows significant accumulation of siRNA-IRDye 700 in the tumor and in the brain at different time points after tail vein injection. All tested bola vesicles (20 mg/kg) contain CHOL and CHEMS.