Figure 8.

Effect of UBE3D on CyclinB1 Protein Expression in hRPE Cells as Determined by Real-Time RT-PCR

mRNA expression levels of UBE3D and CyclinB1 in hRPE cells transfected with overexpression/low expression of UBE3D vectors. Compared with the control groups, the UBE3D mRNA levels were increased, while CyclinB1 levels were reduced in UBE3D-overexpressing cells (∗∗p < 0.01; A). Additionally, the UBE3D mRNA levels were decreased, while CyclinB1 levels were increased in low-UBE3D-expressing cells (∗∗p < 0.01; B).