Table 3. Quality of Life Parameters According to Treatment.
Variable | Total population | Post-matchinga | ||||
---|---|---|---|---|---|---|
TT only (n = 107) | TT-RAI (n = 182) | P value | TT only (n = 100) | TT-RAI (n = 100) | P value | |
SF-12 v2 | ||||||
PCS | 50.44±6.50 | 50.16±6.81 | 0.72 | 50.83±6.45 | 49.40±6.97 | 0.13 |
Physical functioning | 49.19±8.72 | 49.50± 8.15 | 0.76 | 49.74±8.16 | 48.11±8.21 | 0.16 |
Role-physical | 46.94±7.54 | 47.12±8.06 | 0.86 | 47.05±7.55 | 46.46±7.86 | 0.59 |
Bodily pain | 52.25±6.98 | 51.78±8.23 | 0.62 | 52.32±6.66 | 51.33±8.04 | 0.34 |
General health | 49.96±6.33 | 48.82±7.30 | 0.18 | 49.96±6.19 | 48.05±7.29 | <0.05 |
MCS | 48.14±9.24 | 48.13±8.96 | 0.99 | 47.83±9.24 | 47.50±8.34 | 0.78 |
Vitality | 49.71±10.92 | 49.55±10.20 | 0.90 | 49.56±11.04 | 48.97±9.93 | 0.69 |
Social functioning | 51.91±8.57 | 51.77±7.94 | 0.86 | 52.28±7.94 | 51.74±7.81 | 0.63 |
Role-emotional | 45.16±9.93 | 44.80±10.73 | 0.78 | 45.05±9.82 | 43.44±10.22 | 0.26 |
Mental health | 48.88±9.08 | 49.40±9.01 | 0.64 | 48.49±9.25 | 48.66±8.94 | 0.89 |
THYCA-QoL | ||||||
Neuromuscular | 48.21±15.40 | 49.73±16.08 | 0.43 | 48.08±14.60 | 50.83±15.51 | 0.20 |
Voice | 37.73±14.36 | 37.84±16.69 | 0.95 | 37.75±14.10 | 38.25±15.67 | 0.81 |
Concentration | 41.59±16.45 | 38.94±16.00 | 0.18 | 40.50±15.30 | 39.88±16.35 | 0.78 |
Sympathetic | 44.16±17.62 | 45.28±19.13 | 0.62 | 43.75±17.18 | 45.91±19.19 | 0.40 |
Throat/mouth | 38.40±10.60 | 39.84±13.84 | 0.32 | 38.42±10.65 | 40.25±12.37 | 0.26 |
Psychological | 44.04±13.61 | 44.54±14.47 | 0.77 | 43.94±12.79 | 45.69±13.75 | 0.35 |
Sensory | 48.13±19.10 | 49.18±18.33 | 0.65 | 47.88±18.97 | 50.00±18.63 | 0.43 |
Problems with scar | 38.55±21.52 | 35.85±19.20 | 0.27 | 38.25±20.86 | 36.25±19.26 | 0.48 |
Felt chilly | 34.58±15.22 | 38.60±19.05 | 0.05 | 33.50±13.40 | 38.75±19.59 | <0.05 |
Tingling hands/feet | 48.83±17.97 | 50.41±20.60 | 0.51 | 48.25±17.86 | 51.00±20.08 | 0.31 |
Gained weight | 44.86±24.46 | 43.96±22.40 | 0.75 | 45.00±24.36 | 47.75±23.33 | 0.42 |
Headache | 40.65±17.69 | 42.58±19.49 | 0.40 | 40.50±17.69 | 42.50±18.97 | 0.44 |
Less interest in sex | 42.06±18.04 | 42.86±18.50 | 0.72 | 42.25±17.30 | 40.75±16.54 | 0.53 |
Fear of progression | ||||||
Affective reactions | 1.93±0.71 | 1.95±0.83 | 0.86 | 1.94±0.70 | 1.96±0.81 | 0.80 |
Partnership/family | 1.83±0.68 | 1.93±0.92 | 0.30 | 1.84±0.69 | 1.90±0.73 | 0.53 |
Work | 1.53±0.72 | 1.51±0.75 | 0.87 | 1.51±0.73 | 1.44±0.65 | 0.48 |
Loss of autonomy | 1.58±0.62 | 1.61±0.71 | 0.76 | 1.59±0.63 | 1.61±0.67 | 0.84 |
Coping with anxiety | 2.89±0.83 | 3.06±0.94 | 0.13 | 2.89±0.81 | 3.08±0.97 | 0.13 |
Values are expressed as mean±standard deviation.
TT, total thyroidectomy; RAI, radioactive iodine; SF-12, 12-item short-form health survey; PCS, physical component summary score; MCS, mental component summary score; THYCA-QoL, thyroid cancer-specific quality of life.
aSerum thyrotropin was matched between groups.