Table 1.

Developmental status of edible vaccines in clinical trials

Pathogen	Antigen	Host	Use	Clinical trial status	References
Enterotoxigenic E. coli	LT- B	Potato	Diarrhoea	Early phase 1	[104]
Enterotoxigenic E. coli	LT- B	Maize	Diarrhoea	Early phase 1	[105]
Norwalk Virus	CP	Potato	Diarrhoea	Early phase 1	[106]
Rabies Virus	GP/ NP	Spinach	Rabies	Early phase 1	[107]
HBV	HBsAg	Lettuce	Hepatitis B	Early phase 1	[108]
HBV	HBsAg	Potato	Hepatitis B	Phase 1	[109]
Vibrio cholerae	CTB	Rice	Cholera	Phase 1	[110, 111]
HBV	HBV	Saccharomyces cerevisiae	Chronic HBV	Phase 2	[112]
HCV	HCV	Saccharomyces Cerevisiae	Chronic HCV	Phase 2	[113]