Table 3.
Comparison of clinical and laboratory findings in pertussis-positive vs. pertussis-negative infants
| B. pertussis-positive (n = 44) | B. pertussis-negative (n = 128) | p value | |
|---|---|---|---|
| Clinical characteristics | |||
| Paroxysmal cough, n (%) | 17 (38.6) | 44 (34.4) | 0.610 |
| Whooping, n (%) | 13 (29.5) | 35 (27.3) | 0.779 |
| Post tussive vomiting, n (%) | 15 (34.1) | 31 (24.2) | 0.202 |
| Apnea, n (%) | 7 (15.9) | 17 (13.3) | 0.403 |
| Prolonged cough (>14 d), n (%) | 4 (9.1) | 11 (8.6) | 0.92 |
| Wheezing, n (%) | 21 (47.7) | 62 (48.4) | 0.935 |
| Oxygen saturation %, mean ± SD | 95.6 ± 3.8 | 94.0 ± 4.8 | 0.066† |
| Fever >38 °C, n (%) | 6 (13.6) | 21 (16.4) | 0.663 |
| Wang clinical score at admission, mean ± SD | 4.9 ± 1.5 | 5.2 ± 2.5 | 0.689† |
| Duration of hospitalizition, mean ± SD | 5.0 ± 1.9 | 5.8 ± 2.5 | 0.095† |
| Supplemental oxygen therapy, n (%) | 12 (27.3) | 33 (25.8) | 0.846 |
| Duration of oxygen therapy, days, mean ± SD | 0.6 ± 1.0 | 1.1 ± 1.8 | 0.202† |
| Number of infants who required intensive care unit, n (%) | – | 1 (0.78) | |
| Overall disease severity score, mean ± SD | 6.5 ± 1.4 | 6.9 ± 1.6 | 0.095† |
| Laboratory findings | |||
| White blood cell/mm3, mean ± SD | 10,430 ± 2700 | 10,360 ± 4200 | 0.370† |
| Lymphocytes/mm3, mean ± SD | 7180 ± 1650 | 5420 ± 1650 | 0.137† |
| C-reactive protein, mg/dl, mean ± SD | 0.6 ± 0.8 | 0.8 ± 1.4 | 0.306† |
† Mann-Whitney U test, B. pertussis Bordetella pertussis