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. 2020 Mar 18;8(4):e580–e590. doi: 10.1016/S2214-109X(20)30069-3

Table 2.

Cumulative event rate of recurrent stroke, major vascular events, vascular mortality, and all-cause mortality (n=45 732)

28 days 1 year 2 years 3 years 4 years 5 years 6 years 7 years 8 years 9 years
Recurrent stroke
Events 0 5616 8140 9685 10 623 11 298 11 722 11 995 12 161 12 230
No events or death 35 654 24 916 18 535 13 723 9953 7008 4799 2937 1565 668
Deaths 0 655 1067 1391 1634 1786 1910 2002 2064 2077
Censored 0 4467 7912 10 855 13 444 15 562 17 223 18 720 19 864 20 679
Cumulative event rate, % (95% CI) 0 17% (16–17) 26% (25–26) 32% (31–33) 37% (36–37) 41% (41–42) 45% (44–45) 48% (47–49) 51% (50–52) 53% (52–54)
Major vascular event*
Events 0 5963 8731 10 461 11 552 12 324 12 816 13 148 13 346 13 426
No events or death 35 605 24 839 18 448 13 646 9872 6933 4738 2894 1547 660
Deaths 0 347 548 698 807 877 937 975 1001 1005
Censored 0 4456 7878 10 800 13 374 15 471 17 114 18 588 19 711 20 514
Cumulative event rate, % (95% CI) 0 18% (17–18) 27% (27–28) 35% (34–35) 40% (40–41) 45% (45–46) 49% (49–50) 53% (53–54) 57% (56–58) 60% (59–61)
Vascular mortality
Events 0 1208 1972 2597 3113 3545 3885 4105 4284 4362
No events or death 40 370 33 334 27 525 22 097 17 001 12 562 9078 5984 3321 1368
Deaths 0 426 729 962 1168 1298 1416 1496 1550 1569
Censored 0 5402 10 144 14 714 19 088 22 965 25 991 28 785 31 215 33 071
Cumulative event rate, % (95% CI) 0 3% (3–3) 6% (5–6) 8% (8–8) 10% (10–10) 13% (12–13) 15% (15–16) 17% (17–18) 20% (20–21) 23% (22–24)
All-cause mortality
Events 0 1634 2701 3559 4281 4843 5301 5601 5834 5931
No events or death 40 370 33 334 27 525 22 097 17 001 12 562 9078 5984 3321 1368
Censored 0 5402 10 144 14 714 19 088 22 965 25 991 28 785 31 215 33 071
Cumulative event rate, % (95% CI) 0 4% (4–4) 8% (7–8) 11% (10–11) 14% (14–14) 17% (17–18) 21% (20–21) 24% (23–24) 27% (27–28) 30% (30–31)

Time-points are time since first stroke.

*

Stroke, myocardial infarction, and vascular mortality.