Table 1.
Traditional indications and doses for the use of hydroxychloroquine
Indication | Dose | Study |
---|---|---|
Malaria (acute) | 800 mg followed by 400 mg at 6, 24, and 48 h | CDC guidelines[111] |
Rheumatoid arthritis | 400–600 mg/day | Clark et al. [5] |
SLE | 200–400 mg/day | Tsakonas et al. [7], Molad et al. [6] |
Palindromic rheumatism | 200–400 mg/day | Youssef et al. [19] |
Eosinophilic fasciitis | 400 mg/day | Lakhanpal et al. [20] |
Dermatomyositis | 400 mg/day | Woo et al. [21] |
Sjögren’s syndrome | 6–7 mg/kg/day | Fox et al. [22] |
Porphyria cutanea tarda | 250–500 mg/week | Ashton et al. [23], Valls et al. [24] |
Polymorphous light eruption | 200–400 mg/day | Murphy et al. [25] |
Granuloma annulare | 2–9 mg/gk/day | Cannistraci et al. [26] |
Lichen planus | 200–400 mg/day | Eisen [27] |
Lupus panniculitis | 200–400 mg/day | Chung et al. [28] |
Discoid lupus | 400 mg/day | Jessop et al. [29] |
SLE systemic lupus erythematosus