Table 1.
Contraindication | Notes |
---|---|
Multi-system organ failure due to sepsis | |
History of cancer | Except: skin cancer other than melanoma, certain primary brain tumors, remote prostate cancer |
Viral infections | HIV, HTLV I, II, rabies, reactive HbsAg, measles, West Nile virus, SARS, adenovirus, enterovirus, parvovirus, active HSV, VZV, EBV, viral encephalitis/meningitis |
Hepatitis B or C organs can be transplanted into recipients with the same virus | |
CMV + organs can be transplanted- better success if recipient is prophylaxed | |
Bacterial infections | Tuberculosis, gangrenous bowel, bowel perforation, intra-abdominal sepsis |
Fungal infections | Active cryptococcus, aspergillus, Histoplasma, coccidioides, candidemia, invasive yeast infections |
Parasitic infections | Leishmania, trypanosoma, strongyloides, malaria |
Prion disease | CJD, vCJD, fatal familial insomnia, Gerstmann–Straussler Scheinker |
Please confer with your local organ donor organization as some contraindications are relative
HTLV Human T lymphotrophic virus, HbsAg Hepatitis B surface antigen, SARS severe acute respiratory syndrome, HSV herpes simplex virus, VZV varicella zoster virus, EBV Epstein-Barr virus, CMV cytomegalovirus, CJD Creutzfeldt–Jakob disease, vCJD variant Creutzfeldt–Jakob disease