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. 2013 Sep 24;98(5):525–532. doi: 10.1007/s12185-013-1448-z

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© The Japanese Society of Hematology 2013

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Fig. 1 — Time to occlusion after treatment with rFIX, pdFIX, or buffer. Three lots of BAX326 (filled circle) were tested at 75 IU/kg to show lot-to-lot consistency. All lots were considered efficacious as median time to occlusion (3.3–4.8 min) was markedly reduced compared with buffer-treated animals (filled triangle >30 min = no occlusion; P = 0.00035, assessed for Lot 2 only). Median time to occlusion was 4.6 min after treatment with 75 IU/kg of the licensed rFIX (filled square) and 5.1 min after treatment with the licensed pdFIX (filled diamond)