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. 2020 Feb 1;118(6):1502–1510. doi: 10.1016/j.bpj.2020.01.028

Figure 4.

Figure 4

Ferritin shows no measurable heating in response to RF-AMF stimulation. (a) The diagram of the structure of ferritin, comprising a 2-nm-thick protein shell encapsulating a 6- to 8-nm ferrihydrite core, is shown. (b–d) The surface (red) and fluid (blue) temperature monitored for ferritin during RF-AMF application for three frequency regimes, as labeled in the figure, is shown. Each trace denotes the mean ± SEM of 20 runs of RF-AMF stimulation. The RF-AMF application period is denoted by gray shading. A small (<0.2°C) temperature variation from the 440-kHz toroid was measured using a PBS blank and subtracted from (b) (see Fig. S4). To see this figure in color, go online.