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. Author manuscript; available in PMC: 2020 Oct 24.
Published in final edited form as: J Med Chem. 2019 Oct 15;62(20):9246–9253. doi: 10.1021/acs.jmedchem.9b01187

Figure 1.

Figure 1.

Chemical structures of the Mtb20S selective inhibitors. Compounds in the class of 1,3,4-oxathiazol-2-ones and analogs of syringolin 14 are irreversible inhibitors, whereas dipeptide DPLG2 is a noncovalent inhibitor.