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. 2020 Mar 12;2020:8787153. doi: 10.1155/2020/8787153

Figure 4.

Figure 4

XLEP upregulates the ratio of M1/M2 macrophages. (a) The number of M1 and M2 macrophages was determined by immunofluorescence. (b) The levels of TNF-α, IL-6, IL-10, and TGF-β in the culture supernatant of RAW264.7 cells were detected by ELISA. ∗∗P < 0.01 and ∗∗∗P < 0.001 vs. control group. ##P < 0.01 and ###P < 0.001 vs. IL-4 group. ΔP < 0.05 vs. IL-4 + TCM-low group. (c) The expression of Fizz1 and TGM2 in RAW264.7 cells was detected by western blot analysis. ∗∗P < 0.01 and ∗∗∗P < 0.001 vs. control group. ##P < 0.05 and ###P < 0.001 vs. IL-4 group. ΔΔΔP < 0.001 vs. IL-4 + TCM-low group.