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. 2020 Feb 28;15(3):789–798. doi: 10.1021/acschembio.0c00053

Figure 8.

Figure 8

HIV binding and neutralization after SOSIP boosts. (a) Rabbit serum ELISA EC50 IgG titers to BG505T332N SOSIP gp140 trimeric HIV Env protein (12 ng/well), the same strain used for the boost immunizations. Dotted lines indicate the time points of the boost immunizations. (b) TZM-bl neutralization assays against BG505T332N pseudovirus. The dotted line denotes the lowest (20:1) dilution tested in the assay. The three data points on this line represent less than half-maximal inhibition at this dilution. ns denotes p > 0.1 in one-way ANOVA.