Table 2.
Day | EAE score | RR (ms) ± s.d. | SDRR | P SDRR | CV (%) ± s.d. | P CV |
---|---|---|---|---|---|---|
0 | 0 | 102 ± 9 | 5 ± 1 | – | 5 ± 1 | – |
4 | 0 | 112 ± 7 | 5 ± 3 | 0.78 | 4 ± 3 | 0.4 |
8 | 0 | 102 ± 4 | 4 ± 1 | 0.05 | 4 ± 1 | 0.06 |
9 | 1 | 135 ± 9 | 10 ± 4 | 0.002 | 7 ± 3 | 0.04 |
10 | 4 | 94 ± 3 | 3 ± 0.5 | <0.0001 | 3 ± 0.4 | <0.0001 |
11 | 5 | 84 ± 3 | 2 ± 0.5 | <0.0001 | 2 ± 0.6 | <0.0001 |
12 | 5 | 93 ± 2 | 3 ± 1 | 0.001 | 4 ± 1 | 0.01 |
13 | 4 | 82 ± 2 | 2 ± 0.5 | <0.0001 | 2 ± 0.6 | <0.0001 |
15 | 4 | 87 ± 2 | 3 ± 1 | 0.0005 | 4 ± 1 | 0.01 |
17 | 4 | 94 ± 5 | 3 ± 1 | 0.001 | 3 ± 1 | 0.0002 |
Day 0 is the day of EAE induction. RR, mean interval between heartbeats; SDRR, mean s.d. of RR; CV, coefficient of variance (SDRR/RR × 100). P values are for the comparison of SDRR or CV on each day vs. SDRR or CV on day 0.