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. 2008;37(8):361–368. doi: 10.1038/laban0808-361

Table 2.

Time domain analysis of HRV in mouse 4 during the progression of EAE

Day EAE score RR (ms) ± s.d. SDRR P SDRR CV (%) ± s.d. P CV
0 0 102 ± 9 5 ± 1 5 ± 1
4 0 112 ± 7 5 ± 3 0.78 4 ± 3 0.4
8 0 102 ± 4 4 ± 1 0.05 4 ± 1 0.06
9 1 135 ± 9 10 ± 4 0.002 7 ± 3 0.04
10 4 94 ± 3 3 ± 0.5 <0.0001 3 ± 0.4 <0.0001
11 5 84 ± 3 2 ± 0.5 <0.0001 2 ± 0.6 <0.0001
12 5 93 ± 2 3 ± 1 0.001 4 ± 1 0.01
13 4 82 ± 2 2 ± 0.5 <0.0001 2 ± 0.6 <0.0001
15 4 87 ± 2 3 ± 1 0.0005 4 ± 1 0.01
17 4 94 ± 5 3 ± 1 0.001 3 ± 1 0.0002

Day 0 is the day of EAE induction. RR, mean interval between heartbeats; SDRR, mean s.d. of RR; CV, coefficient of variance (SDRR/RR × 100). P values are for the comparison of SDRR or CV on each day vs. SDRR or CV on day 0.