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. 2002 Nov 22;9(12):979–986. doi: 10.1038/sj.cgt.7700539

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© Nature America, Inc. 2002

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Evidence for viral infection in cancer patients: correlation with viral dose. Onyx-015 replication postinfection was measured on day 4 indirectly as described in the legend (Panel A). SCH58500 rAd.p53 gene expression was measured using RT-PCR on biopsies obtained at laparotomy 2–7 days post-HAI (Panel B). The dose at which biological activity was reproducibly seen was similar in the two trials.