Table 3.
Parameters | Control | Normal+ theaflavin (100 mg/kg b.wt) | Diabetes | Diabetes + theaflavin (100 mg/kg b.wt) | Diabetes + metformin (500 mg/kg) |
---|---|---|---|---|---|
Plasma (mg/dl) | |||||
Hexose | 86.09 ± 5.88 | 84.47 ± 5.80 | 137.56 ± 10.24b | 91.47 ± 5.53c | 89.35 ± 5.81 |
Hexosamine | 70.47 ± 6.99 | 68.58 ± 7.03 | 99.34 ± 10.68b | 80.68 ± 8.01c | 78.59 ± 9.18 |
Fucose | 29.43 ± 2.50 | 27.30 ± 2.42 | 42.44 ± 4.26b | 32.39 ± 3.14c | 30.74 ± 2.93 |
Sialic acid | 52.26 ± 4.89 | 50.56 ± 4.92 | 73.51 ± 6.00b | 59.64 ± 5.60c | 58.10 ± 5.69 |
Liver (mg/g) | |||||
Hexose | 29.28 ± 2.61 | 28.59 ± 2.51 | 52.49 ± 5.09b | 32.13 ± 3.21c | 30. 77 ± 2.97 |
Hexosamine | 13.55 ± 1.37 | 12. 48 ± 1.29 | 33.48 ± 2.95b | 18.56 ± 1.61c | 17.17 ± 1.46 |
Fucose | 19.36 ± 1.84 | 20.43 ± 1.78 | 37.53 ± 3.59b | 24.27 ± 2.47c | 22.99 ± 2.26 |
Sialic acid | 11.47 ± 1.04 | 10.81 ± 1.09 | 4.80 ± 0.45b | 9.02 ± 0.85c | 8.26 ± 0.81 |
Kidney (mg/g) | |||||
Hexose | 22.36 ± 2.19 | 21.60 ± 2.01 | 41.87 ± 2.89b | 25.55 ± 2.44c | 24.10 ± 2.22 |
Hexosamine | 18.79 ± 1.35 | 17.70 ± 1.53 | 38.73 ± 2.32b | 22.58 ± 1.63c | 21.74 ± 1.59 |
Fucose | 14.53 ± 1.34 | 13.53 ± 1.37 | 27.63 ± 2.16b | 17.86 ± 1.66c | 16.55 ± 1.86 |
Sialic acid | 7.53 ± 0.61 | 6.85 ± 0.67 | 3.89 ± 0.36b | 5.80 ± 0.56c | 5.27 ± 0.63 |
Values are given as mean ± SD for six animals in each group
Values are considered significantly different at P < 0.05 with post-hoc LSD test *P < 0.05
aControl vs. drug control (theaflavin-alone-treated rats
bControl rats. vs. diabetic rats
cDiabetic rats vs. theaflavin (100 mg/kg)
dDiabetic rats treated with theaflavin 100 mg/kg vs. metformin (500 mg/kg