Table 3.
Causes of respiratory failure
| Cause of respiratory failure | Entire cohort n = 125 | Neutrophil recovery prior to IMV n = 72 | Neutrophil recovery on IMV n = 26 | Never achieved neutrophil recovery n = 27 |
|---|---|---|---|---|
| Pneumonia/Pulmonary infectiona | 33 (26%) | 19 (26%) | 9 (35%) | 5 (19%) |
| Shock/Hemodynamic instability | 26 (21%) | 11 (15%) | 3 (12%) | 12 (44%) |
| Pulmonary hemorrhage | 22 (18%) | 12 (17%) | 6 (23%) | 4 (15%) |
| Fluid overload | 19 (15%) | 12 (17%) | 4 (15%) | 3 (11%) |
| Hypoxia without identified infection or other causeb | 6 (5%) | 3 (4%) | 1 (4%) | 2 (7%) |
| Altered mental status | 4 (3%) | 4 (6%) | 0 (0%) | 0 (0%) |
| Idiopathic pneumonia syndrome | 2 (2%) | 2 (3%) | 0 (0%) | 0 (0%) |
| Upper airway obstruction/mucositis | 2 (2%) | 0 (0%) | 2 (8%) | 0 (0%) |
| Pericardial effusion | 1 (1%) | 1 (1%) | 0 (0%) | 0 (0%) |
| Pulmonary hypertension | 1 (1%) | 1 (1%) | 0 (0%) | 0 (0%) |
| Unknown/not reported | 9 (7%) | 7 (10%) | 1 (4%) | 1 (4%) |
Data are presented in frequencies and (%) with percentages rounded to the nearest whole number
aPulmonary infections included infections from any pathogen (ie bacterial, viral or fungal pathogens)
bThese subjects had hypoxia or ARDS as the cause of respiratory failure with other clear etiology listed on this table