Skip to main content
. 2012 Dec 3;48(6):819–824. doi: 10.1038/bmt.2012.241

Table 2.

Evolution of pulmonary function testing in BOS patients according to the lung function phenotype

Mean±s.d. N (%) Phenotype 1 a N (%) Phenotype 2 b P-value N (%) Total BOS
FEV1, L
 Diagnosis 53 1.649±0.882 24 1.922±0.635 0.07 77 1.734±0.819
 Last 46 1.849±0.975 20 2.094±0.864 0.24 66 1.923±0.943
FEV1, % pred
 Diagnosis 53 50.9±21.8 24 61.3±11.5 0.01 77 54.1±19.7
 >50% 25 (47%) 21 (88%)
 30–50% 20 (38%) 2 (8%)
 <30% 8 (15%) 1 (4%)
 Last 46 58.7±26.9 20 65.5±21.8 0.33 66 60.7±25.5
 >50% 29 (63%) 16 (80%)
 30–50% 10 (22%) 2 (10%)
 <30% 7 (15%) 2 (10%)
FVC, L
 Diagnosis 53 2.811±1.173 24 2.426±0.822 0.26 77 2.692±1.085
 Last 46 2.815±1.113 20 2.750±1.058 0.91 66 2.796±1.089
FVC, % pred
 Diagnosis 53 71.2±22.0 24 65.6±14.5 0.32 77 69.4±20.0
 Last 46 76.9±25.5 20 72.9±22.3 0.60 66 75.7±24.5
TLC, L
 Diagnosis 47 5.737±1.587 24 4.643±1.309 0.008 71 5.367±1.578
 Last 36 5.612±1.861 16 4.688±1.320 0.04 52 5.327±1.753
TLC, % pred
 Diagnosis 47 98.5±21 24 87.6±15.2 0.03 71 94.8±19.8
 Last 36 101.1±26.4 16 84.9±12.8 0.001 52 96.1±24.1

Abbreviations: BOS=bronchiolitis obliterans syndrome; FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity; pred=predicted; TLC=total lung capacity.

aFEV1/FVC ratio <0.7.

bFEV1/FVC ratio >0.7.