Table 1.
Body weight, adiposity, and plasma measurements in rats fed with standard diet (SD) or high-fat diet (HFD) for 6 weeks
| SD | HFD | |
|---|---|---|
| Initial body weight (g) | 305 ± 2.2 (n = 9) | 301 ± 3.0 (n = 10) |
| Final body weight (g) | 408 ± 2.3 (n = 9) | 426 ± 3.9* (n = 10) |
| Epididymal adipose tissue (g/100 g body wt.) | 0.73 ± 0.04 (n = 9) | 1.13 ± 0.08* (n = 10) |
| Retroperitoneal adipose tissue (g/100 g body wt.) | 0.61 ± 0.03 (n = 9) | 0.97 ± 0.03* (n = 10) |
| Mesenteric adipose tissue (g/100 g body wt.) | 0.55 ± 0.07 (n = 9) | 0.96 ± 0.11* (n = 10) |
| Total cholesterol (mg/dl) | 60 ± 2.0 (n = 6) | 80 ± 2.5* (n = 6) |
| HDL (mg/dl) | 22 ± 0.4 (n = 8) | 22 ± 1.4 (n = 8) |
| TGL (mg/dl) | 39 ± 2.6 (n = 8) | 56 ± 5.0* (n = 8) |
| Blood glucose (mg/dl) | 91 ± 2.3 (n = 7) | 109 ± 2.4* (n = 7) |
| Kitt (%/min) | 3.7 ± 0.1 (n = 7) | 2.7 ± 0.3* (n = 7) |
| Leptin (ng/ml) | 1.0 ± 0.2 (n = 4) | 4.5 ± 1.2* (n = 4) |
All values are presented as means±SEM; Student t-test. Kitt (%/min): percentage of plasma glucose concentration decline per minute. Total cholesterol, HDL, TGL, and leptin levels were measured after 12 h fasting and glucose levels after 8 h fasting
HDL high-density lipoprotein, TGL triacylglycerol
*Different from SD; P < 0.05