Fig. 2.
Loess spline curves of long-term LVEF trajectories based on etiology. a Patients from ischemic aetiology of HF; diabetic (orange) vs. non-diabetic (blue) patients. P value for trajectory changes on LVEF < 0.001 for both groups. P for comparison between groups (interaction between trajectory changes and diabetes) < 0.001. Shaded regions displayed around curves represent the confidence interval at level = 0.95. b Patients from non-ischemic aetiologies. P value for trajectory changes on LVEF < 0.001 for both groups. P for comparison between groups (interaction between trajectory changes and diabetes) = 0.18. Shaded regions displayed around curves represent the confidence interval at level = 0.95