Table 4.

MCID estimates for the EQ-5D utility index and anchor

	Estimated value for MCID
Anchor	MCID	(95% CI)	Correlation coefficienta
2–3 CAT total score changes	0.021–0.031	(0.018–0.035)	0.651
8 EQ-VAS score changes	0.033	(0.027–0.040)	0.581
5–10% FEV1 predicted changes	0.017–0.033	(0.012–0.042)	0.422
The pooled MCID estimateb	0.028	(0.023–0.034)	NA

MCID minimal clinically important differences, CI confidence interval, FEV₁ forced expiratory volume in 1 s

^aThe relevance of each anchor to the EQ-5D utility index was computed as Spearman’s rank correlation coefficient

^bthe pooled estimation was calculated as weighted mean using the correlation coefficient between the EQ-5D utility index and each anchor