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Apoptotic and cytotoxic effects of IFN-α1b/IFN-α2b on PBMCs. (A) Analysis of apoptosis was performed by flow cytometry after IFN-α1b/IFN-α2b (0, 1000 U/ml) treatment for 48 h (n=4). (B) Cytotoxicity was evaluated by LDH release after treatment with IFN-α1b/IFN-α2b (0, 1000 U/ml) for 48 h (n=4). Statistical analyses were performed with the Wilcoxon matched-pairs signed rank test (ns – not significant).
