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. 2020 Mar 23;21:24. doi: 10.1186/s12910-020-00465-7

Table 4.

Mentions, rejections and endorsements of positive reasons (Category P)

Positive Reasons (Category P)
P.1: The creation of chimeras may advance basic research

Mention [23, 35, 54, 71, 79]

Reject [8, 72]

Endorse [9, 12, 13, 17, 41, 42, 5961, 75, 76, 81, 82]

P.2: The creation of chimeras may produce benefits for humans
P.2.i: New therapies might be developed on the basis of chimera research

Mention [8, 20, 41, 43, 54, 66, 71, 79, 84]

Reject [11, 22, 23]

Endorse [2, 9, 12, 13, 17, 34, 35, 39, 42, 55, 60, 67, 72, 75, 85]

P.2.ii: Chimeras might serve as sources of transplantable organs and tissues

Mention [5, 63]

Reject [none]

Endorse [2, 4, 34, 41, 42, 51, 60, 66, 72, 85]

P.2.iii: Chimera research might open ways to human enhancement

Mention [80]

Reject [none]

Endorse [81]

P.3: The creation of chimeras may prevent direct harm to humans or animalsa

Mention [12, 23, 66]

Reject [none]

Endorse [13, 41, 42]

P.4: The creation of chimeras may have other benefitsb

Mention [46, 80]

Reject [none]

Endorse [13]

a E.g. by helping to replace human subjects or laboratory animals in biomedical research

b E.g. by fostering the preservation of endangered species, or by allowing animal enhancement