Table 2:
Vehicle N=9 |
Calcium N=6 |
H2O2 N=7 |
Calcium + H2O2 N=3 |
|
---|---|---|---|---|
Complex I substrate- Pyruvate + malate | ||||
State 3 | 212±5 | 139±13 * | 216±7 | 144±10 * † |
State 4 | 70±3 | 61±5 † | 81±3 | 62±5 † |
RCR | 3.1±0.2 | 2.3±0.2* † | 2.7±0.1 | 2.4±0.1* † |
Complex II substrate- Succinate + Rotenone | ||||
State 3 | 435±17 | 308±30 * † | 451±13 | 318±24 * † |
State 4 | 171±14 | 135±11 | 158±6 | 131±11 |
RCR | 2.7±0.2 | 2.3±0.2 | 2.9±0.1 | 2.4±0.1 |
Mean ± SEM;
p<0.05 vs. vehicle;
p<0.05 vs. H2O2 alone;
analysis by one-way ANOVA.