Table 1:
KidneyMELD at LT <50% (N=33,499) |
KidneyMELD at LT ≥50% (N=1,421) |
p-value | |
---|---|---|---|
Male gender, % | 65.9 | 66.0 | 0.9 |
Age at LT, median (IQR) | 55 (48-61) | 58 (53-63) | <0.001 |
Liver disease, % | <0.001 | ||
HCV | 32.1 | 31.0 | |
Alcohol | 24.7 | 27.4 | |
NASH | 21.0 | 28.7 | |
AI disease* | 14.2 | 6.9 | |
HBV | 2.4 | 2.0 | |
Other | 5.8 | 4.0 | |
MELD-Na at LT, median (IQR) | 27 (21-34) | 27 (20-31) | <0.001 |
Albumin at LT, median (IQR) | 2.9 (2.4-3.4) | 3.1 (2.7-3.6) | <0.001 |
Diabetes, % | 23.0 | 39.4 | <0.001 |
Ascites, % | <0.001 | ||
None | 11.7 | 7.5 | |
Mild | 48.5 | 40.9 | |
Moderate | 39.9 | 51.7 | |
Location prior to LT, % | <0.001 | ||
Home | 58.9 | 52.8 | |
Inpatient ward | 26.2 | 29.6 | |
Inpatient intensive care | 15.0 | 17.7 | |
Dialysis at LT, % | 11.4 | 41.5 | <0.001 |
Waiting time, median (IQR) | 40 (11-156) | 43 (10-163) | 0.2 |
Donor age, median (IQR) | 43 (27-55) | 45 (28-57) | <0.001 |
DCDD organ, % | 5.6% | 6.1% | 0.4 |
Abbreviations: AI – auto-immune; DCDD – donation after circulatory determination of death; DDLT – deceased donor liver transplantation; HBV – hepatitis B virus; HCV – hepatitis C virus; IQR – interquartile range; KidneyMELD – proportion of MELD-Na score attributable to creatinine; LT – liver transplantation; MELD-Na – Model for End-stage Liver Disease Sodium score; NASH – non-alcoholic steatohepatitis
Includes: auto-immune hepatitis, primary sclerosing cholangitis and primary biliary cholangitis