Fig. 1.
Structure of the catalytic domain (CpNanICD) of Clostridium perfringens in complex with 2-(cyclohexylamino)ethanesulfonic acid (CHES): CpNanICD-CHES. (A) A ribbon diagram of CpNanICD-CHES structure. CHES and residues are displayed as stick representation. (B) Chemical structure of CHES. (C) Stereoview of CHES binding mode in the CpNanICD catalytic site. A water molecule (W1) is shown as a red sphere. Hydrogen bonds are shown as dashed lines. The composite omit map (mFo-DFc) of CHES is contoured at 1.5 σ and displayed as mesh (green). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)