Table 2.
The comparison of genetic parameters of HCV HVR1 quasispecies profiles derived from either 1.38 kb or 9.1 kb amplicons
| Sample | Amplicon | Number of clones | Genetic complexity |
Genetic distance |
|||
|---|---|---|---|---|---|---|---|
| Nucleotide | Amino acid | d | dS | dN | |||
| LIV19 | 1.38 kb fragment | 11 | 0.770 | 0.685 | 0.026 | 0.022 | 0.028 |
| 9.1 kb fragment (LRP) | 16 | 0.537* | 0.800* | 0.025* | 0.036* | 0.020* | |
| LIV23 | 1.38 kb fragment | 18 | 0.430 | 0.430 | 0.164 | 0.098 | 0.197 |
| 9.1 kb fragment (LRP) | 15 | 0.620* | 0.829** | 0.113* | 0.144* | 0.101* | |
Star and double star indicate p > 0.05 and p < 0.05, respectively, comparing to corresponding genetic parameters derived from the 1.38 kb amplicon.