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. 2006 Jul 21;348(1):245–252. doi: 10.1016/j.bbrc.2006.07.069

Fig. 6.

Fig. 6

DMS footprinting assays of AES SARS 1. Lane 1, 31-mer thrombin-inhibiting aptamer with K+; lane 2, 31-mer thrombin-inhibiting aptamer without K+; lane 3, AES SARS 1 with K+; lane 4, AES SARS 1 without K+; lane 5, AES SARS 1 hybridized with its target DNA in the presence of K+; lane 6, AES SARS 1 containing the 15-mer control DNA in the presence of K+. The methylated guanines in the G-quartet structure are shown in the secondary structure attached to AES SARS 1. The experimental conditions are described in the Materials and methods.