Fig 4. eIF5AHyp expression pattern in the spleen of control and T2D.
eIF5AHyp is expressed in immune cells in the spleen. We evaluated expression of eIF5AHyp in Pax5+ B cells, CD4+ T cells and CD8+ T cells in the spleens of donors with T2D and controls matched for age, gender and BMI. Most eIF5AHyp+ cells co-expressed Pax5+ (A,D); however, a select group of eIF5AHyp+ cells expressed either CD4+ (B,E) or CD8+ (C,F).