Table 2. Species associated with control (n = 25) vs. SS (n = 25).
| Name | Relative abundancea | LEfSe | Spearman’s rho | ||
|---|---|---|---|---|---|
| Control | SS | LDA Score | P | ||
| Streptococcus_HQ748137_s | 0.83 (4.16) | 2.32 (19.49) | 4.53 | 0.012 | - 0.44* |
| Prevotella histicola | 0.06 (4.48) | 0.86 (10.46) | 4.33 | 0.016 | 0.27 |
| Streptococcus_HQ762034_s | 0.63 (9.11) | 1.64 (8.20) | 4.31 | 0.026 | - 0.28 |
| Streptococcus parasanguinis | 1.11 (4.94) | 1.92 (3.56) | 4.28 | 0.028 | - 0.49* |
| Streptococcus_4P003152_s | 0.26 (4.11) | 0.80 (4.24) | 4.08 | 0.004 | - 0.21 |
| Streptococcus_uc | 0.68 (3.45) | 1.15 (1.49) | 4.07 | 0.012 | - 0.41* |
| Actinomyces_4P002811_s | 0.07 (0.90) | 0.33 (3.27 | 3.77 | 0.012 | - 0.35 |
| Streptococcus anginosus | 0.02 (1.44) | 0.11 (8.08) | 3.72 | 0.082 | - 0.19 |
| Streptococcus mutans | 0.00 (0.19) | 0.03 (7.14) | 3.56 | 0.026 | - 0.19 |
| Haemophilus_HQ807753_s | 0.01 (0.10) | 0.08 (2.81) | 3.46 | 0.044 | 0.39 |
| Veillonella parvula | 0.01 (0.17) | 0.08 (3.20) | 3.45 | 0.020 | - 0.17 |
| Prevotella_FM995711_s | 0.00 (3.28) | 0.02 (2.25) | 3.44 | 0.016 | 0.11 |
| Streptococcus sobrinus | 0.00 (0.03) | 0.00 (4.55) | 3.42 | 0.048 | - 0.28 |
| Atopobium parvulum | 0.03 (0.90) | 0.12 (1.21) | 3.37 | 0.064 | - 0.05 |
| Prevotella salivae | 0.01 (1.00) | 0.11 (1.15) | 3.33 | 0.032 | 0.24 |
| Lactobacillus salivarius | 0.00 (0.06) | 0.00 (2.44) | 3.32 | 0.030 | 0.15 |
| Veillonella rodentium | 0.01 (0.22) | 0.06 (1.28) | 3.21 | 0.010 | 0.10 |
| Streptococcus intermedius | 0.01 (0.13) | 0.04 (1.36) | 3.18 | 0.078 | - 0.08 |
| Haemophilus haemolyticus | 0.00 (0.25) | 0.00 (0.78) | 2.85 | 0.040 | 0.33 |
| Lactobacillus fermentum | 0.00 (0.00) | 0.00 (0.69) | 2.79 | 0.002 | NA |
| Prevotella_4P003758_s | 0.00 (0.18) | 0.02 (0.52) | 2.70 | 0.008 | - 0.23 |
| Prevotella_4P005351_s | 0.00 (0.38) | 0.01 (0.29) | 2.67 | 0.040 | 0.15 |
| Treponema denticola | 0.00 (0.64) | 0.00 (0.08) | 2.51 | 0.050 | - 0.01 |
| Saccharimonas_AM420132_s | 0.00 (0.43) | 0.00 (0.05) | 2.53 | 0.010 | 0.22 |
| Leptotrichia_FJ976402_s | 0.01 (0.21) | 0.00 (0.05) | 2.53 | 0.002 | 0.11 |
| DQ241813_g_DQ241813_s | 0.02 (0.21) | 0.00 (0.09) | 2.55 | 0.028 | 0.09 |
| Eikenella corrodens | 0.02 (0.19) | 0.00 (0.09) | 2.56 | 0.002 | 0.29 |
| Neisseria_AY005028_s | 0.00 (0.35) | 0.00 (0.03) | 2.60 | 0.030 | - 0.16 |
| Campylobacter showae | 0.01 (0.31) | 0.00 (0.04) | 2.62 | 0.000 | 0.17 |
| Leptotrichia hofstadii | 0.01 (0.24) | 0.00 (0.06) | 2.65 | 0.018 | 0.23 |
| Prevotella shahii | 0.00 (0.30) | 0.00 (0.08) | 2.66 | 0.028 | 0.20 |
| AM420062_g_AM420062_s | 0.00 (0.45) | 0.00 (0.20) | 2.79 | 0.082 | 0.12 |
| Prevotella nigrescens | 0.01 (0.73) | 0.00 (0.07) | 2.80 | 0.000 | 0.73** |
| Stomatobaculum longum | 0.03 (0.33) | 0.00 (0.27) | 2.85 | 0.020 | 0.22 |
| AF432141_g_AF432141_s | 0.00 (1.32) | 0.00 (0.00) | 2.87 | 0.004 | 0.28 |
| Capnocytophaga gingivalis | 0.04 (0.48) | 0.00 (0.04) | 2.88 | 0.000 | - 0.21 |
| Leptotrichia wadei | 0.02 (1.02) | 0.00 (0.11) | 2.91 | 0.002 | 0.09 |
| Capnocytophaga leadbetteri | 0.00 (0.87) | 0.00 (0.11) | 2.92 | 0.034 | 0.08 |
| Leptotrichia hongkongensis | 0.03 (1.24) | 0.00 (0.27) | 2.96 | 0.048 | - 0.04 |
| Neisseria_uc | 0.05 (0.53) | 0.00 (0.41) | 2.98 | 0.002 | 0.20 |
| Oribacterium asaccharolyticum | 0.04 (1.08) | 0.00 (0.33) | 3.03 | 0.024 | 0.30 |
| Halomonas hamiltonii | 0.00 (1.99) | 0.00 (0.00) | 3.05 | 0.020 | 0.08 |
| Saccharimonas_AF385520_s | 0.03 (1.06) | 0.00 (0.34) | 3.11 | 0.020 | 0.27 |
| Corynebacterium matruchotii | 0.07 (1.47) | 0.00 (0.57) | 3.12 | 0.016 | 0.29 |
| Lachnoanaerobaculum orale | 0.09 (0.60) | 0.04 (0.24) | 3.16 | 0.026 | - 0.13 |
| Streptococcus_HQ757980_s | 0.04 (2.00) | 0.13 (0.37) | 3.19 | 0.020 | - 0.19 |
| Veillonella rogosae | 0.09 (0.69) | 0.01 (0.22) | 3.19 | 0.002 | 0.58** |
| Leptotrichia_DQ447842_s | 0.06 (1.55) | 0.00 (0.70) | 3.32 | 0.022 | 0.36 |
| Porphyromonas gingivalis | 0.01 (2.22) | 0.00 (0.17) | 3.38 | 0.034 | - 0.21 |
| Campylobacter concisus | 0.07 (2.73) | 0.00 (0.21) | 3.42 | 0.002 | 0.43* |
| Porphyromonas_AM420091_s | 0.08 (3.51) | 0.00 (2.28) | 3.53 | 0.030 | 0.06 |
| Neisseria oralis | 0.01 (4.81) | 0.00 (0.31) | 3.54 | 0.046 | 0.18 |
| Haemophilus sputorum | 0.07 (4.44) | 0.00 (0.15) | 3.57 | 0.000 | 0.44* |
| Neisseria elongata | 0.14 (2.36) | 0.00 (2.40) | 3.60 | 0.004 | 0.36 |
| Neisseria sicca group | 0.07 (6.68) | 0.00 (0.64) | 3.72 | 0.034 | 0.06 |
| Rothia aeria | 0.29 (3.44) | 0.04 (1.09) | 3.74 | 0.016 | 0.02 |
| Lautropia mirabilis | 0.10 (6.46) | 0.00 (0.24) | 3.82 | 0.000 | 0.44* |
| Fusobacterium periodonticum | 0.68 (2.72) | 0.03 (3.67) | 3.94 | 0.008 | 0.16 |
| Streptococcus sanguinis | 1.03 (5.92) | 0.35 (2.85) | 4.13 | 0.012 | 0.30 |
| Streptococcus_CP006776_s | 1.96 (16.7) | 0.59 (6.65) | 4.53 | 0.022 | 0.06 |
| Neisseria perflava | 0.79 (50.2) | 0.00 (11.03) | 4.81 | 0.004 | 0.19 |
| Neisseria subflava | 3.71 (33.7) | 0.02 (31.99) | 4.82 | 0.002 | 0.35 |
| Haemophilus parainfluenzae | 3.54 (32.7) | 1.22 (9.75) | 4.84 | 0.022 | 0.42* |
aExpressed as the median (range)
*, P < 0.05;
**, P < 0.01