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. 2020 Feb 28;10:71. doi: 10.3389/fcimb.2020.00071

Table 6.

Association of growth forms of Gardnerella spp. and Lactobacillus species in relation to clinical characteristics in BV-positive women (Ison-Hay criteriaa).

Bacterial growth form HIV status UTI symptoms Abnormal discharge
HIV-negative (%) (n = 19) HIV-positive (%) (n = 31) ORb (95% CI) p-value Absent (%) (n = 37) Present (%) (n = 13) ORc (95% CI) p-value Absent (%) (n = 40) Present (%) (n = 10) ORd (95% CI) p-value
Gardnerella spp.
Absent 2 (11e) 3 (10) Reff 1.0g 3 (8e) 2 (15) Reff 0.60g 5 (13e) 0 (0) Reff 0.57g
Dispersed 0 (0) 0 (0) -h - 0 (0) 0 (0) - - 0 (0) 0 (0) - -
Biofilm 17 (89) 28 (90) - - 34 (92) 11 (85) - - 35 (88) 10 (100) - -
Lactobacillus species
Absent 1 (5e) 8 (26) Reff 0.065g 7 (19e) 2 (15) Reff 0.11g 7 (18e) 2 (20) Reff 0.86g
Dispersed 15 (79) 22 (71) - - 29 (78) 8 (62) - - 29 (73) 8 (80) - -
Biofilm 3 (16) 1 (3) - - 1 (3) 3 (23) - - 4 (10) 0 (0) - -
a

Class IV and 0 omitted for comparison with Nugent scoring.

b

Odds ratio (95% confidence interval) adjusted by pregnancy status; Exposure: bacterial growth forms; outcome: HIV-negative vs. HIV-positive; Entering significance level of 0.05; Removing significance level of 0.1; only significant OR was displayed.

c

Odds ratio (95% confidence interval) adjusted by pregnancy status; Exposure: bacterial growth forms; outcome: UTI symptoms absent vs. UTI symptoms present; Entering significance level of 0.05; Removing significance level of 0.1; only significant OR was displayed.

d

Odds ratio (95% confidence interval) adjusted by pregnancy status; Exposure: bacterial growth forms; outcome: abnormal vaginal discharge absent vs. abnormal vaginal discharge present; Entering significance level of 0.05; Removing significance level of 0.1; only significant OR was displayed.

e

Column percentage between bacterial growth forms.

f

Used as reference category for OR.

g

Fisher's exact test.

h

Not available or not applicable.