. Author manuscript; available in PMC: 2020 Mar 24.

Published in final edited form as: J Toxicol Environ Health A. 2018 Nov 12;81(22):1186–1198. doi: 10.1080/15287394.2018.1544523

Table 4.

Female-specific associations between the TLR2-rs 696480 polymorphisms and lung function in different age groups using age cut-offs at 40, 45 and 50 years (N = 103).

Lung Function	Comparison in female workers^* (Polymorphisms - Wild-type)
Lung Function	Difference (STE)	Difference (STE)
	Age cut-off at 40 years
	<40 years	≥40 years
	(N = 67)	(N = 36)
FEV1, L	3.71 (0.08)^†	−0.31 (0.26)
FVC, L	0.30 (0.10)^†	0.40 (0.28)
	Age cut-off at 45 years
	<45 years	≥45 years
	(N = 82)	(N = 21)
FEV1, L	0.30 (0.09)^†	0.10 (0.28)
FVC, L	0.30 (0.10)^†	−0.04 (0.38)
	Age cut-off at 50 years
	<50 years	≥50 years
	(N = 94)	(N = 9)
FEV1, L	0.30 (0.10)^†	N/A
FVC, L	0.30 (0.10)^†	N/A

^*:

p values were from multivariate models adjusting for height, weight and smoking habit.

^†:

Significant after adjusting for multiple comparison at α = 0.007 (0.05/7).