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. 2020 Feb 29;12(5):4222–4229. doi: 10.18632/aging.102875

Table 1. Biological processes according to GO that were common for TSIX, BEST1 and ADAMTSL4 in the FRA group.

ADAMTSL4 in FRA, BEST1 in FRA, TSIX in FRA 103 immune system process (GO:0002376) regulation of cellular macromolecule
biosynthetic process (GO:2000112) organic cyclic compound biosynthetic
process (GO:1901362) cellular macromolecule metabolic process
(GO:0044260) negative regulation of biosynthetic process (GO:0009890)
cellular biosynthetic process (GO:0044249) negative regulation of RNA
metabolic process (GO:0051253) cellular process (GO:0009987)
macromolecule metabolic process (GO:0043170) positive regulation of
macromolecule metabolic process (GO:0010604) negative regulation of
RNA biosynthetic process (GO:1902679) negative regulation of
transcription, DNA-templated (GO:0045892) detection of chemical stimulus
involved in sensory perception of smell (GO:0050911) cellular component
organization or biogenesis (GO:0071840) response to organic substance
(GO:0010033) intracellular signal transduction (GO:0035556) detection of
chemical stimulus involved in sensory perception (GO:0050907) nitrogen
compound metabolic process (GO:0006807) regulation of RNA biosynthetic
process (GO:2001141) positive regulation of cellular process (GO:0048522)
cellular response to stress (GO:0033554) nucleic acid-templated transcription
(GO:0097659) positive regulation of cellular metabolic process
(GO:0031325) biological regulation (GO:0065007) positive regulation of
transcription, DNA-templated (GO:0045893) positive regulation of nucleic
acid-templated transcription (GO:1903508) RNA metabolic process
(GO:0016070) biological process (GO:0008150) regulation of multicellular
organismal process (GO:0051239) cellular aromatic compound metabolic
process (GO:0006725) regulation of cellular process (GO:0050794)
Unclassified (UNCLASSIFIED) organic cyclic compound metabolic process
(GO:1901360) gene expression (GO:0010467) positive regulation of cellular
biosynthetic process (GO:0031328) detection of chemical stimulus
(GO:0009593) negative regulation of cellular macromolecule biosynthetic
process (GO:2000113) cellular macromolecule biosynthetic process
(GO:0034645) primary metabolic process (GO:0044238) biosynthetic
process (GO:0009058) organic substance biosynthetic process (GO:1901576)
cellular nitrogen compound metabolic process (GO:0034641) regulation of
developmental process (GO:0050793) positive regulation of gene expression
(GO:0010628) cellular response to stimulus (GO:0051716) regulation of
macromolecule metabolic process (GO:0060255) positive regulation of
protein metabolic process (GO:0051247) negative regulation of gene
expression (GO:0010629) regulation of cellular metabolic process
(GO:0031323) positive regulation of biological process (GO:0048518)
positive regulation of nitrogen compound metabolic process (GO:0051173)
metabolic process (GO:0008152) regulation of nitrogen compound metabolic
process (GO:0051171) positive regulation of RNA biosynthetic process
(GO:1902680) negative regulation of cellular process (GO:0048523)
negative regulation of biological process (GO:0048519) apoptotic process
(GO:0006915) negative regulation of macromolecule biosynthetic process
(GO:0010558) macromolecule biosynthetic process (GO:0009059)
localization (GO:0051179) regulation of transcription, DNA-templated
(GO:0006355) nucleobase-containing compound metabolic process
(GO:0006139) sensory perception of chemical stimulus (GO:0007606)
hematopoietic or lymphoid organ development (GO:0048534) regulation of
catalytic activity (GO:0050790) regulation of response to stress
(GO:0080134) small molecule metabolic process (GO:0044281) negative
regulation of nucleic acid-templated transcription (GO:1903507) detection of
stimulus involved in sensory perception (GO:0050906) RNA biosynthetic
process (GO:0032774) sensory perception of smell (GO:0007608) cellular
component assembly (GO:0022607) positive regulation of macromolecule
biosynthetic process (GO:0010557) cellular component organization
(GO:0016043) regulation of cellular biosynthetic process (GO:0031326)
immune system development (GO:0002520) positive regulation of metabolic
process (GO:0009893) detection of stimulus (GO:0051606) regulation of
metabolic process (GO:0019222) developmental process (GO:0032502)
positive regulation of molecular function (GO:0044093) nucleic acid
metabolic process (GO:0090304) leukocyte activation (GO:0045321)
heterocycle biosynthetic process (GO:0018130) transcription, DNA-
templated (GO:0006351) regulation of macromolecule biosynthetic process
(GO:0010556) regulation of biological process (GO:0050789) regulation of
gene expression (GO:0010468) regulation of nucleic acid-templated
transcription (GO:1903506) cell activation (GO:0001775) regulation of
nucleobase-containing compound metabolic process (GO:0019219)
regulation of RNA metabolic process (GO:0051252) positive regulation of
RNA metabolic process (GO:0051254) regulation of biosynthetic process
(GO:0009889) cellular metabolic process (GO:0044237) heterocycle
metabolic process (GO:0046483) sensory perception (GO:0007600)
regulation of immune system process (GO:0002682) positive regulation of
biosynthetic process (GO:0009891) regulation of primary metabolic process
(GO:0080090) organic substance metabolic process (GO:0071704)
regulation of molecular function (GO:0065009) positive regulation of
nucleobase-containing compound metabolic process (GO:0045935)