Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 11;12(5):4527–4546. doi: 10.18632/aging.102907

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Mao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

LncRNA-LALR1 upregulates SNORD72 and ID2 in HCC cells. (A) qRT-PCR showing the expression of SNORD72 and ID2 after lncRNA-LALR1 silencing in SMMC-7721 cells. (B) Western blot showing the expression of ID2 after lncRNA-LALR1 silencing in SMMC-7721 cells. (C) qRT-PCR showing the expression of SNORD72 and ID2 after knockdown of lncRNA-LALR1 in HepG2 cells. (D) Western blot showing the expression of ID2 after lncRNA-LALR1 silencing in HepG2 cells. (E) FISH assay showing the expression of SNORD72 after lncRNA-LALR1 silencing in SMMC-7721 cells. (F) FISH assay showing the expression of ID2 after lncRNA-LALR1 silencing in SMMC-7721 cells. (G) FISH showing lncRNA-LALR1 is co-localized with SNORD72 in HepG2, SMMC-7721, PLC/PRF/5, Sk-Hep1 cells. (H) RNA pulldown assay showing lncRNA-LALR1 interacts with SNORD72 and ID2 mRNA. (I) The effect of lncRNA-LALR1 on the mRNA stability of ID2. (J) The effect of lncRNA-LALR1 on the mRNA stability of SNORD72. *: P < 0.05; **: P < 0.01; ***: P < 0.001; ns: no significant.