Table 1. Correlation between lncRNA-LALR1 expression and clinicopathological features in cancer tissues from 46 HCC patients.
Factors | No. of patients (%) | LncRNA-LALR1# | χ2 value | P value | |
low(n=35) | high(n=11) | ||||
No. of patients (%) | No. of patients (%) | ||||
Gender | 0.558 | 0.455 | |||
Male | 36(78.3) | 26(72.2) | 10(27.8) | ||
Female | 10(21.7) | 9(90.0) | 1(10.0) | ||
Age(years) | 0 | 1 | |||
≤ 50 | 14(30.4) | 11(78.6) | 3(21.4) | ||
>50 | 32(69.6) | 24(75.0) | 8(25.0) | ||
Size(cm) | 0.537 | 0.464 | |||
≤ 5 | 27(58.7) | 19(70.4) | 8(29.6) | ||
>5 | 19(41.3) | 16(84.2) | 3(15.8) | ||
HBsAg | 0.287 | 0.592 | |||
Negative | 8(17.4) | 5(62.5) | 3(37.5) | ||
Positive | 38(82.6) | 30(78.9) | 8(21.1) | ||
AFP (ng/ml) | 0.717 | 0.397 | |||
≤ 20 | 18(39.1) | 12(66.7) | 6(33.3) | ||
> 20 | 28(60.9) | 23(82.1) | 5(17.9) | ||
ALB (g/L) | 0.157 | 1 | |||
≤ 35 | 3(6.5) | 2(66.7) | 1(33.3) | ||
>35 | 43(93.5) | 33(76.7) | 10(23.3) | ||
Liver cirrhosis | 0 | 1 | |||
No | 20(43.5) | 15(75.0) | 5(25.0) | ||
Yes | 26(56.5) | 20(76.9) | 6(23.1) | ||
Tumor number | 0.406 | 0.524 | |||
Single | 32(69.6) | 23(71.9) | 9(28.1) | ||
Multiple | 14(30.4) | 12(85.7) | 2(14.3) | ||
T stage | 0.004 | 0.949 | |||
I+II | 31(67.4) | 23(74.2) | 8(25.8) | ||
III+IV | 15(32.6) | 12(80.0) | 3(20.0) | ||
N stage | 1.647 | 0.199 | |||
Negative | 34(73.9) | 28(82.4) | 6(17.6) | ||
Positive | 12(26.1) | 7(58.3) | 5(41.7) | ||
TNM stage | 8.073 | 0.033 | |||
I | 12(26.1) | 11(91.7) | 1(8.3) | ||
II | 6 (13.0) | 5(83.3) | 1(16.7) | ||
III | 12(26.1) | 11(91.7) | 1(8.3) | ||
IV | 16(34.8) | 8(50.0) | 8(50.0) | ||
Vascular invasion | 0.323 | 0.57 | |||
Negative | 37(80.4) | 27(73.0) | 10(27.0) | ||
Positive | 9(19.6) | 8(88.9) | 1(11.1) | ||
Lymphnode metastasis | 0.008 | 0.927 | |||
No | 36(78.3) | 28(77.8) | 8(22.2) | ||
Yes | 10(21.7) | 7(70.0) | 3(30.0) | ||
Distant metastasis | 8.509 | 0.004 | |||
No | 37(80.4) | 32(86.5) | 5(13.5) | ||
Yes | 9(19.6) | 3(33.3) | 6(66.7) | ||
Differentiation | 5.195 | 0.048 | |||
Well | 7(15.2) | 6(85.7) | 1(14.3) | ||
Moderate | 35(76.1) | 28(80.0) | 7(20.0) | ||
Poor | 4(8.7) | 1(25.0) | 3(75.0) |
Chi-square test was used to evaluate the correlation between lncRNA-LALR1 expression and clinicopathological features. The bold values indicated that the P value was smaller than 0.05.