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. 2020 Mar 11;12(5):4527–4546. doi: 10.18632/aging.102907

Table 1. Correlation between lncRNA-LALR1 expression and clinicopathological features in cancer tissues from 46 HCC patients.

Factors No. of patients (%) LncRNA-LALR1# χ2 value P value
low(n=35) high(n=11)
No. of patients (%) No. of patients (%)
Gender 0.558 0.455
 Male 36(78.3) 26(72.2) 10(27.8)
 Female 10(21.7) 9(90.0) 1(10.0)
Age(years) 0 1
 ≤ 50 14(30.4) 11(78.6) 3(21.4)
 >50 32(69.6) 24(75.0) 8(25.0)
Size(cm) 0.537 0.464
 ≤ 5 27(58.7) 19(70.4) 8(29.6)
 >5 19(41.3) 16(84.2) 3(15.8)
HBsAg 0.287 0.592
 Negative 8(17.4) 5(62.5) 3(37.5)
 Positive 38(82.6) 30(78.9) 8(21.1)
AFP (ng/ml) 0.717 0.397
 ≤ 20 18(39.1) 12(66.7) 6(33.3)
 > 20 28(60.9) 23(82.1) 5(17.9)
ALB (g/L) 0.157 1
 ≤ 35 3(6.5) 2(66.7) 1(33.3)
 >35 43(93.5) 33(76.7) 10(23.3)
Liver cirrhosis 0 1
 No 20(43.5) 15(75.0) 5(25.0)
 Yes 26(56.5) 20(76.9) 6(23.1)
Tumor number 0.406 0.524
 Single 32(69.6) 23(71.9) 9(28.1)
 Multiple 14(30.4) 12(85.7) 2(14.3)
T stage 0.004 0.949
 I+II 31(67.4) 23(74.2) 8(25.8)
 III+IV 15(32.6) 12(80.0) 3(20.0)
N stage 1.647 0.199
 Negative 34(73.9) 28(82.4) 6(17.6)
 Positive 12(26.1) 7(58.3) 5(41.7)
TNM stage 8.073 0.033
 I 12(26.1) 11(91.7) 1(8.3)
 II 6 (13.0) 5(83.3) 1(16.7)
 III 12(26.1) 11(91.7) 1(8.3)
 IV 16(34.8) 8(50.0) 8(50.0)
Vascular invasion 0.323 0.57
 Negative 37(80.4) 27(73.0) 10(27.0)
 Positive 9(19.6) 8(88.9) 1(11.1)
Lymphnode metastasis 0.008 0.927
 No 36(78.3) 28(77.8) 8(22.2)
 Yes 10(21.7) 7(70.0) 3(30.0)
Distant metastasis 8.509 0.004
 No 37(80.4) 32(86.5) 5(13.5)
 Yes 9(19.6) 3(33.3) 6(66.7)
Differentiation 5.195 0.048
 Well 7(15.2) 6(85.7) 1(14.3)
 Moderate 35(76.1) 28(80.0) 7(20.0)
 Poor 4(8.7) 1(25.0) 3(75.0)

Chi-square test was used to evaluate the correlation between lncRNA-LALR1 expression and clinicopathological features. The bold values indicated that the P value was smaller than 0.05.