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. 2020 Mar 3;12(5):4424–4444. doi: 10.18632/aging.102894

Table 2. Univariate and multivariate analysis of OS in patients with ccRCC.

Parameters Univariate analysis Multivariate analysis
P HR 95%CI P HR 95%CI
Lower Upper Lower Upper
Age(Continuous) 0.4410 1.1280 0.8306 1.5310
Gender
Male 1.0000
Female 0.8190 1.0380 0.7555 1.4260
Tumor stage
T1/T2 1.0000
T3/T4 <0.0001 3.2030 2.3470 4.3680 0.8367 0.9364 0.5014 1.7490
Metastasis
No 1.0000
yes <0.0001 4.4130 3.2270 6.0350 <0.0001 2.6229 1.7469 3.9380
Pathological stage
I/II 1.0000
III/IV <0.0001 3.8760 2.8010 5.3630 0.0071 2.6986 1.3103 5.5580
Histological grade
G1/G2 1.0000
G3/G4 0.0236 1.4390 1.0500 1.9720 0.0780 0.7172 0.4956 1.0380
SNHG3 0.0008 2.4240 2.0543 2.9474 0.0362 1.3401 1.0556 1.7010
SNHG4 0.0178 1.3300 1.0510 1.6830 0.4216 1.1586 0.8091 1.6590
SNHG5 0.0011 0.7783 0.6698 0.9044 0.0631 0.8366 0.6931 1.0100
SNHG8 0.0146 0.7908 0.6551 0.9547 0.6159 0.9400 0.7382 1.1970
SNHG12 0.2140 1.0980 0.9473 1.2730
SNHG15 0.1050 1.1830 0.9655 1.4510
SNHG17 0.1630 1.1810 0.9349 1.4910
SNHG25 0.1590 1.1240 0.9550 1.3240