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. 2020 Mar 13;12(5):4573–4591. doi: 10.18632/aging.102913

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Copyright © 2020 Cao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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High APEX1 expression predicts poor prognosis in HCC patients, including those with grade 1 tumors. (A–D) Kaplan-Meier survival curve analysis shows OS, DSS, PFS and RFS rates of high and low APEX1 expressing HCC patients, respectively. (E) Kaplan-Meier survival curve analysis of 5-year OS probability of 55 tumor grade 1 HCC patients is shown. (F) Kaplan-Meier survival curve analysis of the 5-year OS rate of HCC patients with stage 1 cancer is shown. The hazard ratio (HR) was calculated based on the Cox Proportional-Hazards model.