Table 1. RNAseq analysis results of the main factors involved in angiogenesis and migration regulated by GUSBP5-AS overexpression.
Gene_id | Log2FoldChange | Stat | p value | p adj | Significant |
MMP9 | 1.680414704 | 4.19413 | 2.74E-05 | 0.000111 | Ups |
FGF2 | 1.381545685 | 3.44619 | 0.000569 | 0.001783 | Ups |
MMP2 | 1.22681 | 2.06987 | 0.0008 | 0.005605 | Ups |
FOXO1 | 1.232851707 | 5.50857 | 3.62E-08 | 2.35E-07 | Ups |
RNAseq analysis was performed after EPCs infection with LV5-NC and GUSBP5-AS lentivirus, and three groups of LV5-NC and three groups of GUSBP5-AS were detected; Gene id means differentially expressed genes; p value was calculated by t test, and p adj was obtained by p value normalized by Benjamini-Hochberg; significant means the up- or down-regulation of the gene expressed in the GUSBP5-AS overexpression group compared with the LV5-NC.