Table 1.
Baseline patient demographics and clinical characteristics by adherence levels for 306 patients in the medication arm of the Collaborative Initial Glaucoma Treatment Study (CIGTS)
| 0 Missed (n=142) |
≤⅓ Missed (n=112) |
⅓-⅔ Missed (n=31) |
≥⅔ Missed (n=21) |
||
|---|---|---|---|---|---|
| Baseline Variables | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | P-value* |
| Age (years) | 58.5 (11.0) | 57.9 (11.3) | 56.4 (9.7) | 48.4 (10.8) | 0.0001 |
| MD (dB) | −4.7 (4.1) | −5.2 (3.9) | −6.7 (5.3) | −6.3 (5.3) | 0.0057 |
| IOP (mmHg) | 27.7 (5.5) | 26.7 (5.0) | 29.7 (6.8) | 28.2 (5.8) | 0.2388 |
| CESD Score | 2.1 (3.4) | 2.0 (3.4) | 4.5 (4.6) | 4.3 (5.2) | <0.0001 |
| # (%) | # (%) | # (%) | # (%) | P-value* | |
| Gender | |||||
| Male | 82 (57.8) | 58 (51.8) | 15 (48.4) | 9 (42.9) | 0.3904 |
| Female | 60 (42.2) | 54 (48.2) | 16 (51.6) | 12 (57.1) | |
| Race | |||||
| White/Other | 92 (64.8) | 70 (62.5) | 17 (54.8) | 7 (33.3) | 0.0268 |
| Black | 50 (35.2) | 42 (37.5) | 14 (45.2) | 14 (66.7) | |
| Marital Status | |||||
| Married | 86 (60.6) | 67 (59.8) | 12 (38.7) | 9 (42.9) | 0.0065 |
| Not Married | 56 (39.4) | 45 (40.2) | 19 (61.3) | 12 (57.1) | |
| Education | |||||
| ≤HS | 68 (47.9) | 65 (58.0) | 17 (54.8) | 14 (66.7) | 0.0229 |
| Some College+ | 74 (52.1) | 47 (42.0) | 14 (45.2) | 7 (33.3) | |
| Depression | |||||
| CESD<7 | 121 (87.7) | 99 (91.7) | 21 (67.7) | 15 (71.4) | 0.0004 |
| CESD≥7 | 17 (12.3) | 9 (8.3) | 10 (32.3) | 6 (28.6) |
SD, standard deviation; MD, mean deviation; dB, decibels; IOP, intraocular pressure; mmHg, millimeters of mercury; CESD, Center for Epidemiologic Studies Depression Scale; HS, high school
*
Regression analysis to test for a linear relationship (for continuous variables) or difference (for dichotomous variables)