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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Hum Genet. 2019 Sep 25;139(9):1183–1196. doi: 10.1007/s00439-019-02058-w

Figure 2.

Figure 2

Examples of applications of placental DNAme in assessing and improving maternal and fetal health. These include: detecting altered DNAme linked to in utero exposures; detecting placental-specific DNAme signatures in maternal blood; quantifying maternal immune cells infiltrating the placenta; subclassifying placental phenotypes into more homogenous groups; diagnosing chromosomal imbalance or imprinting errors; and using methylation changes linked to disease to identify nearby predisposing SNPs (mQTLs).