Fig. 2.

Increasing LOX expression following differentiation into M2-like macrophages. (A and B) M0 macrophages were treated with IL-4 and IL-13 (20 ng/ml each) for the indicated times. The expression of LOX was detected by real-time RT-PCR (n = 3) and Western blotting (n = 3) (*p<0.05, **p<0.01 vs 0 h). (C) M0 macrophages were pre-treated with or without ActD (2 ng/ml) for 30 min before the treatment with IL-4 and IL-13 (20 ng/ml each). After the treatment, LOX expression was detected by real-time RT-PCR (n = 3) (**p<0.01). Graphs show data as the mean ± SD.