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. 2020 Mar 13;11(1):1–19. doi: 10.4291/wjgp.v11.i1.1

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Histological presentation in rats with suprahepatic ligation of the inferior vena cava. Assessment (stained with hematoxylin-eosin, magnification x 10, scare bar: 50 µm) was at 48 h post-ligation, in controls (upper) and BPC 157-treated rats (lower), stomach (left upper, control; lower, BPC 157), duodenum (right upper, control; lower, BPC 157). Note, substantial congestion and dilatation of mucosal and submucosal capillaries, submucosal edema, ischemic changes, such as architectural distortion and foci of hemorrhage with fibrin deposition in controls (upper), which were markedly counteracted in BPC 157-treated rats (lower).