Table 2.
LOECs of PFOS and PFOA for the different activity parameters (mean spike rate (MSR), mean burst rate (MBR) and mean network burst rate (MNBR)) on the different cell models. – Indicates no LOEC could be defined.
| MSR | MBR | MNBR | ||||
|---|---|---|---|---|---|---|
| PFOS | PFOA | PFOS | PFOA | PFOS | PFOA | |
| Rat primary cortical neurons | 100 µM | — | 100 µM | — | — | — |
| iCell Glutaneuron – iCell Astrocytes co-culture | 0.1 µM | 1 µM | 100 µM | 10 µM | 0.1 µM | 1 µM |
| SynFire iNS co-culture | 100 µM | — | 100 µM | — | — | — |