Table 3.
Description of different metric parameters.
| Metric parameter | Description |
|---|---|
| Mean spike rate (MSR) | Total number of spikes divided by recording time (Hz) |
| ISI coefficient of variation | Standard deviation ISI (time between spikes) divided by the mean ISI. Measure for spike regularity: 0 indicates perfect spike distribution, >1 signals bursting |
| Mean burst rate (MBR) | Total number of bursts divided by recording time (Hz) |
| Burst duration | Average time from the first spike in a burst till the last spike (s) |
| Number of spikes per burst | Average number of spikes occurring in a burst |
| Mean inter-spike interval (ISI) within burst | Mean inter-spike interval within a burst (s) |
| Inter-burst interval (IBI) | Time between the last spike of a burst and the first spike of a subsequent burst (s) |
| IBI coefficient of variation | Standard deviation of IBI divided by the mean IBI. Measure for burst regularity |
| Burst percentage | Percentage of total number of spikes occurring in a burst |
| Mean network burst rate (MNBR) | Total number of network bursts divided by recording time (Hz) |
| Network burst duration | Average time from the first spike till the last spike in a network burst (s) |
| Number of spikes per network burst | Average number of spikes occurring in a network burst |
| Mean ISI within network burst | Average of the mean ISIs within a network burst (s) |
| Number of spikes per network burst per channel | Average number of spikes across the network bursts in the network burst divided by the number of electrodes participating in the network burst |
| Network burst percentage | Percentage of total spikes occurring in a network burst |
| Network IBI coefficient of variation | Standard deviation of network IBI divided by the mean network IBI. Measure of network burst rhythmicity: value is small when bursts occur at regular interval and increases when bursts occur more sporadic |
| Network normalized duration IQR | Interquartile range of network bursts durations. Measure for network burst duration regularity: larger values indicate wide variation in duration. |
| Area under normalized cross-correlation | Area under inter-electrode cross-correlation normalized to the auto-correlations. The higher the value, the greater the synchronicity of the network |
| Full width at half height (FWHH) of normalized cross-correlation | Width at half height of the normalized cross-correlogram. Measure for network synchrony: the higher the value, the less synchronized the network is |
Adapted from56.