Table 2.

The functional analysis of nsSNPs using SIFT, PolyPhen-2, and SNAP2.

		SIFT		PolyPhen-2		SNAP2
SNP ID	AA change	Score	Predicted effect	Score	Predicted effect	Score	Predicted effect	Expected accuracy%
rs2032582	S893A	1.00	Tolerated	0.000	Benign	−50	Neutral	72
rs6314	H452Y	0.02	Affect protein function	0.010	Benign	−11	Neutral	57
rs6265	V66M	0.18	Tolerated	0.822	Possibly damaging	−41	Neutral	72
rs1065852	P34S	0.00	Affect protein function	0.946	Possibly damaging	66	Effect	80
rs2228479	V92M	0.28	Tolerated	0.015	Benign	58	Effect	75
rs11580409	L1056V	1.00	Tolerated	0	Benign	−78	Neutral	87
rs6280	G9S	0.24	Tolerated	0	Benign	−28	Neutral	61
rs12603700	G335E	0.07	Tolerated	0.844	Possibly damaging	0	Neutral	53
rs3889402	A204S	0.00	Affect protein function	0	Benign	−13	Neutral	57
rs3810651	I478F	0.00	Affect protein function	0.662	Possibly damaging	67	Effect	80
rs4680	V158M	0.09	Tolerated	0.016	Benign	−8	Neutral	53
rs117986340	G999C	0.00	Affect protein function	1.000	Probably damaging	5	Effect	53
rs2072446	S205L	0.11	Tolerated	0.008	Benign	10	Effect	59