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. 2020 Mar 18;11:291. doi: 10.3389/fphar.2020.00291

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Copyright © 2020 Liang, Yu, Huang and Yen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Sensitization and treatment protocols for the experimental mice, nasal symptom and immunoglobulin levels. (B,C) Cytokines expression of CD4+ splenocytes and nasal lymphoid tissues. (D) Decreased eosinophil infiltration in Hematoxylin and eosin staining of tissue sections from experimental mice. AR = allergic rhinitis group; Dex = allergic mice treated with 1 mg/kg dexamethasone; LO10 = allergic mice treated with 10 mg/kg luteolin; LO30 = allergic mice treated with 30 mg/kg luteolin; ^#P < 0.05 vs. blank group; *P < 0.05 vs. AR group.